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Nutrimartus
CETYL MYRISTOLEATE
DESCRIPTION
Cetyl myristoleate, also known as CM, is an ester of the fatty acid
myristoleic acid (cis-9- tetradecenoic acid). It occurs in
significant amounts in nature in the oil glands of male beavers and in
mice. CM is made by reacting myristoleic acid (derived from beef
marrow) with cetyl alcohol. Harry Diehl, a researcher at the National
Institutes for Health, isolated cetyl myristoleate from the Swiss Albino
mouse, while looking for causes and treatments for arthritis. He has
received 2 U.S. Patents on cetyl myristoleate. Cetyl
myristoleate has the formula CH3 (CH2)15 OCO (CH2)7 CH =CH (CH2)3 CH3. Its
chemical name is cis-9-myristoleate.
PHYSIOLOGY/ PHARMACOLOGY
Both components of CM, cetyl alcohol and myristoleic acid, may increase
lubrication and resilience of cartilage or other tissues. CM may also
inhibit the lipoxygenase pathway of leucotriene production from archadonic
acid. The C4,D4, and E4 pro-inflammatory leucotrienes stimulate antigen
-antibody reactions such as broncho- and vaso-constriction. The B4
leucotrienes attract white blood cells; a high concentration of white may
benefit from more. About one out of three people may find that continued
supplementation at ten to twenty percent of the original amount is
supportive in maintaining good nutritional status. It is also possible to
deliver CM through the skin on the affected joints, using liposome
technology in a cream base. As additional support; use as desired.
BIO-ENHANCING AGENTS
We recommend taking other nutritional supplements such as glucosamine (HCl
or sulfate) and chondroitin sulfate, flax seed oil, primrose oil,
methylsulfonylmethane(MSM), sea cucumber, green lipped mussel extracts,
medium chain triglycerides(MCT), cartilage, collagen, copper salicylate
and antioxidents, along with CM, to address the full range of causes of
cartilage degradation. Many of the nutrients can be combined in formulas.
Lecithin (to help emulsify the CM) and lipase (to help digest it) are
helpful for people who blood cells may be associated with the attacks on
the body tissues in the vicinity, which may be related to auto-immune
reactions.
INDICATIONS
As a dietary supplement, for nutritional support for inflammatory
conditions including osteoarthritis, rheumatoid arthritis, psoriatic
arthritis, prostatitis, ulcerative colitis, irritable bowel syndrome,
fibromyalgia, tendonitis, and bursitis. CM is not indicated for
inflammation associated with recent injury, but it may be indicated for
support of joints prone to deterioration due to whiplash or other
hyper-extension/compression injuries. CM and other dietary supplements
such as flax seed oil and primrose oil may be indicated for nutritional
support for auto-immune reactions.
DIRECTIONS FOR USE
Softgels: three 260 mg elemental CM softgels daily, split between
breakfast and dinner.
Powder: 600 to 1000 mg elemental CM daily, split between breakfast and
dinner.
Nutritional benefits vary. Most people will find that 12 to 18 grams
elemental CM over three to four weeks is appropiate. Larger people have
difficulty digesting oils. We recommend minimizing caffeine, alcohol, red
meats, steroids, and refined sugar, flour, salt, and possibly foods in the
nightshade family for anyone with arthritis. Drink lots of distilled
water, and eat lots of fiber and bioflavonoid-rich fruit and vegetables.
TOXICITY, CAUTIONS, & CONTRAINDICATIONS
No toxicity or contraindications have been noted. If gastric upset
occurs, decrease the amount for a few days and slowly increase back to the
recommended amount, or take lecithin and lipase to aid in digestion.