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BOSWELLIA
COMMON NAME
Boswellia, frankincense; in Ayurveda: salai guggal
LATIN NAME
Boswellia serrata
DESCRIPTION
Boswellia, or salai guggal extract is a standardized powder extract of
the gum of the Boswellia tree (Boswellia serrata), containing a
mixture of Boswellic acids. The Boswellia tree is a balsamic tree that
secretes aromatic oleoresins which are collected, when they dry, into a
gum, after exuding from cuts in the bark.
BIOCHEMISTRY
Four pentacyclic triterpene acids, including beta-boswellic acid, have
been identified as causing the anti-inflammatory and anti-arthritic
actions of extracts of Boswellia serrata. Boswellic acids appear to
inhibit the 5-lipoxygenase pathway by which Arachadonic acid is converted
to Leukotrienes. Boswellic acids do not appear to inhibit the other two
enzymes which metabolize Arachadonic acid, 12-lipoxygenase and
cyclooxygenase. By contrast, conventional non-steroidal anti-inflammatory
drugs (NSAIDS) appear to inhibit the cyclooxygenase pathway by which
Arachadonic acid is converted to Prostaglandins and Thromboxanes.
PHYSIOLOGY/PHARMACOLOGY
Boswellic acids are effective anti-inflammatory and anti-arthritic
agents, for both osteoarthritis and rheumatoid arthritis, soft tissue
rheumatism, and low back pain. They also help control excessively high
blood lipids and atherosclerosis, and protect the liver against bacterial
galactosamine-endotoxins. The non-acid part of the gum has pain-relieving
and sedative qualities, and in high doses can lower blood pressure, and
reduce heart rate in dogs but increase it in frogs. Observed benefits of
Boswellia include reduction in joint swelling, increased mobility, steroid
sparing action (less steroids required in combined treatment), less
morning stiffness, improved grip strength, and general improvement in
quality of life, for both osteoarthritis and rheumatoid arthritis.
INDICATIONS
Osteoarthritis and rheumatoid arthritis, soft tissue rheumatism, low
back pain.
DIRECTIONS FOR USE
Three 250 mg capules per day, between meals.
BIO-ENHANCING AGENTS
Glucosamine sulfate, chondroitin sulfate, EPA (Eicosapentaenoic acid)
from flax seed oil or fish oil, Evening Primrose oil and DLPA
(dl-Phenylalanine); Vitamins B6, C and E; Manganese, Selenium and Zinc;
isolated soy protein and other soy foods; Turmeric and alpha-Lipoic acid.
TOXICITY, CAUTIONS & CONTRAINDICATIONS
Safe for human and animal use.
